Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532944 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL9534457 | 0.82 | MAPT (0.45) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL9531843 | 0.81 | PPARG (0.37) | ALDH1A1MAPTKMT2AMEN1MAOB | |
| SCHEMBL9530770 | 0.80 | MAPT (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL8021379 | 0.80 | CYP3A4 (0.49) | ALDH1A1MAPTKMT2AMEN1MAOB | |
| SCHEMBL8650153 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTKMT2AMEN1MAOB | |
| SCHEMBL8980424 | 0.79 | KMT2A (0.44) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL9531639 | 0.76 | KMT2A (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL8177483 | 0.75 | KMT2A (0.39) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL9533182 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |