Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533372 | 0.91 | KDM1A (0.34) | TSHR | |
| SCHEMBL9531663 | 0.89 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL22499372 | 0.82 | — | — | |
| SCHEMBL29791692 | 0.77 | PARP1 (0.36) | CA1CA2PARP1 | |
| SCHEMBL18440156 | 0.77 | PARP1 (0.36) | CA1CA2PARP1 | |
| SCHEMBL2581169 | 0.71 | MAOB (0.33) | TSHR | |
| SCHEMBL18440302 | 0.70 | PARP1 (0.34) | TSHRCA1CA2PARP1 | |
| SCHEMBL18440606 | 0.70 | PARP1 (0.34) | TSHRCA1CA2PARP1 | |
| SCHEMBL29174116 | 0.70 | MAOB (0.32) | — | |
| SCHEMBL9532397 | 0.68 | NPSR1 (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |