Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174116 | 0.98 | MAOB (0.32) | MAOBHTR2AKMT2ANOTUMALDH1A1 | |
| SCHEMBL28990007 | 0.92 | NOTUM (0.31) | NOTUM | |
| SCHEMBL28990003 | 0.92 | ALDH1A1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL7883341 | 0.77 | MAOB (0.39) | MAOBHTR2ATSHRNOTUMALDH1A1 | |
| SCHEMBL1697644 | 0.77 | PARP1 (0.36) | MAOBHTR2AKMT2AALDH1A1 | |
| SCHEMBL9530955 | 0.74 | KMT2A (0.38) | HTR2AKMT2ATSHRALDH1A1 | |
| SCHEMBL9532397 | 0.73 | NPSR1 (0.37) | MAOBHTR2AKMT2ATSHRALDH1A1 | |
| SCHEMBL9533537 | 0.71 | TSHR (0.31) | TSHR | |
| SCHEMBL9531388 | 0.71 | ALOX12 (0.36) | MAOBHTR2AKMT2A | |
| SCHEMBL9532066 | 0.70 | ALOX12 (0.34) | MAOBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876366-B1 | ANGIOGENESIS INHIBITING PYRIDAZINAMINES | JANSSEN PHARMACEUTICA NV (BE) | 2001-07-25 | — | — | EP | claimed |
| US-5985878-A | Angiogenesis inhibiting pyridazinamines | JANSSEN PHARMACEUTICALS, N.V. (BE) | 1999-11-16 | — | — | US | claimed |
| EP-0876366-A2 | ANGIOGENESIS INHIBITING PYRIDAZINAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-11-11 | — | — | EP | claimed |
| WO-1997026258-A1 | ANGIOGENESIS INHIBITING PYRIDAZINAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-07-24 | — | — | WO | claimed |
| EP-0277384-A2 | 1H-imidazole-5-carboxylic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-10 | — | — | EP | claimed |
| EP-2763528-A1 | PESTICIDE PREPARATION AND PROCESS FOR PRODUCING THE SAME | Bayer Intellectual Property GmbH (DE) | 2014-08-13 | — | — | EP | disclosed |
| US-8586611-B2 | Fungicidal carboxamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-19 | — | — | US | disclosed |
| EP-1948649-B1 | FUNGICIDAL CARBOXAMIDES | DU PONT (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2013050433-A1 | PESTICIDE PREPARATION AND PROCESS FOR PRODUCING THE SAME | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-11 | — | — | WO | disclosed |
| CN-101501083-B | Method for preparing high viscosity fluid | EXXON MOBIL CHEM PATENTS INC | 2012-12-05 | — | — | CN | disclosed |
| US-20110269712-A1 | Fungicidal Carboxamides | BISAHA JOHN JOSEPH | 2011-11-03 | — | — | US | disclosed |
| CN-101522647-A | Substituted azolin-2-yl-amino compounds | BASF AG (DE) | 2009-09-02 | — | — | CN | disclosed |
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-5135927-A | 2-chloro-4-trifluoromethylthiazol-5-carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-4992434-A | Prevention of infestation of plants by phytopathogenic microorganisms | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |
| EP-0277384-A2 | 1H-imidazole-5-carboxylic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-10 | — | — | EP | disclosed |
| US-4076726-A | Amidino-hydrazone derivatives | AKZONA INCORPORATED (US) | 1978-02-28 | — | — | US | disclosed |
| US-4028380-A | Hydrazino-imidazole derivatives | AKZONA INCORPORATED (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269712-A1 | Fungicidal Carboxamides | NAT1, PFAS, CHRM1 | MAOB 2045/4885HTR2A 2824/4885KMT2A 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.