Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804851 | 0.87 | MAPK1 (0.56) | TDP1MAPK1CYP3A4TRPA1CSNK2A1 | |
| SCHEMBL10316838 | 0.83 | MAPK1 (0.46) | TDP1MAPK1CYP3A4TRPA1CSNK2A1 | |
| SCHEMBL6472011 | 0.82 | CYP3A4 (0.54) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL9530566 | 0.82 | MAPK1 (0.46) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL282107 | 0.81 | MAPK1 (0.61) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL9529407 | 0.79 | TDP1 (0.39) | TDP1MAPK1CYP3A4TRPA1CSNK2A1 | |
| SCHEMBL9776985 | 0.77 | CYP3A4 (0.38) | TDP1MAPK1CYP3A4TRPA1CSNK2A1 | |
| SCHEMBL17593306 | 0.75 | CYP3A4 (0.39) | TDP1MAPK1CYP3A4TRPA1RORC | |
| SCHEMBL1555247 | 0.74 | MAPK1 (0.56) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL19461641 | 0.74 | RXRA (0.46) | TDP1MAPK1CYP3A4TRPA1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371240-B1 | USE OF N-PHENYL-SUBSTITUTED OXAZINDIONES AS HERBICIDES AND N-PHENYL-SUBSTITUTED OXAZINDIONES AND SOME PROCESSES FOR THEIR PRODUCTION | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5164498-A | Herbicidal N-phenyl-substituted oxazinediones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5061310-A | HERBICIDAL N-PHENYL-SUBSTITUTED OXAZINEDIONES AND OXAZINONETHIONES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0371240-A1 | Use of N-phenyl-substituted oxazindiones as herbicides and N-phenyl-substituted oxazindiones and some processes for their production | BAYER AG (DE) | 1990-06-06 | — | — | EP | disclosed |
| EP-0290902-A2 | Condensed (thio)hydantoins | BAYER AG (DE) | 1988-11-17 | — | — | EP | disclosed |