SCHEMBL9529407

SCHEMBL9529407

CC(C)Oc1cc(N=C=O)c(Cl)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PPOX P50336 2/20 0.39
NR1I2 O75469 1/20 0.39
CSNK2A1 P68400 2/20 0.38
RORC P51449 1/20 0.38
GAA P10253 2/20 0.38
MAPK1 P28482 2/20 0.37
CYP3A4 P08684 4/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 3/20 0.37
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TRPA1 O75762 1/20 0.35
CYP1A2 P05177 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7021771 0.86 PPOX (0.40) TDP1MEN1KMT2APPOXNR1I2
SCHEMBL9529910 0.81 MEN1 (0.39) TDP1MEN1KMT2AGAAMAPK1
SCHEMBL9836900 0.81 ALDH1A1 (0.51) TDP1MEN1KMT2AGAAMAPK1
SCHEMBL11804851 0.79 MAPK1 (0.56) TDP1MEN1KMT2ACSNK2A1RORC
SCHEMBL9533540 0.79 TDP1 (0.56) TDP1MEN1KMT2APPOXNR1I2
SCHEMBL9835474 0.78 TDP1 (0.38) TDP1MAPK1CYP3A4ALDH1A1HPGD
SCHEMBL9835490 0.77 KDM4E (0.39) TDP1PPOXNR1I2RORCMAPK1
SCHEMBL8485314 0.76 CUL4A (0.44) TDP1MEN1KMT2ARORCGAA
SCHEMBL1493025 0.75 TDP1 (0.52) TDP1MAPK1CYP3A4ALDH1A1HPGD
SCHEMBL16606252 0.75 CSNK2A1 (0.52) TDP1MEN1KMT2APPOXNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0371240-B1 USE OF N-PHENYL-SUBSTITUTED OXAZINDIONES AS HERBICIDES AND N-PHENYL-SUBSTITUTED OXAZINDIONES AND SOME PROCESSES FOR THEIR PRODUCTION BAYER AG (DE) 1993-06-16 EP disclosed
US-5164498-A Herbicidal N-phenyl-substituted oxazinediones BAYER AKTIENGESELLSCHAFT (DE) 1992-11-17 US disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-5061310-A HERBICIDAL N-PHENYL-SUBSTITUTED OXAZINEDIONES AND OXAZINONETHIONES BAYER AKTIENGESELLSCHAFT (DE) 1991-10-29 US disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
EP-0371240-A1 Use of N-phenyl-substituted oxazindiones as herbicides and N-phenyl-substituted oxazindiones and some processes for their production BAYER AG (DE) 1990-06-06 EP disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed