Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740787 | 0.92 | CA4 (0.46) | CA2CA4CYP3A4TSHRNFKB1 | |
| Methylamine SCHEMBL9540584 | 0.90 | CA2 (0.43) | CA2CA4CYP3A4TSHRNFKB1 | |
| Potassium Ion SCHEMBL7154954 | 0.87 | CA4 (0.42) | CA2CA4CTSLSLC22A16CPT2 | |
| Cetyl Alcohol SCHEMBL17986422 | 0.85 | CA2 (0.41) | CA2TSHRCA1 | |
| Tetrylammonium SCHEMBL6315154 | 0.85 | CA4 (0.34) | CA2CA4CTSLSLC22A16CPT2 | |
| SCHEMBL671816 | 0.79 | RECQL (0.44) | CA2TSHRCA1 | |
| SCHEMBL29913440 | 0.77 | SLC22A6 (0.35) | CA2CA4 | |
| Butane SCHEMBL20204269 | 0.76 | CYP3A4 (0.43) | CA2CA4CYP3A4TSHRNFKB1 | |
| SCHEMBL181245 | 0.75 | CA2 (0.39) | CA2CA4CTSLSLC22A16CPT2 | |
| SCHEMBL4903344 | 0.75 | CA4 (0.33) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550652-A1 | DETERGENT COMPOSITIONS CONTAINING ALKYL ETHOXY CARBOZYLATES AND POLYHYDROXY FATTY ACID AMIDES. | PROCTER & GAMBLE (US) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006157-A1 | DETERGENT COMPOSITIONS CONTAINING ALKYL ETHOXY CARBOZYLATES AND POLYHYDROXY FATTY ACID AMIDES | THE PROCTER & GAMBLE COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |