Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.39 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690847 | 0.88 | RECQL (0.40) | RECQLCES2GLAHPGDTSHR | |
| SCHEMBL28709042 | 0.88 | RECQL (0.40) | RECQLCES2GLAHPGDTSHR | |
| SCHEMBL671818 | 0.88 | RECQL (0.40) | RECQLCES2GLAHPGDTSHR | |
| SCHEMBL28690849 | 0.88 | RECQL (0.40) | RECQLCES2GLAHPGDTSHR | |
| SCHEMBL31402373 | 0.88 | RECQL (0.40) | RECQLCES2GLAHPGDTSHR | |
| SCHEMBL8000985 | 0.87 | RECQL (0.39) | RECQLCES2GLAHPGDTSHR | |
| SCHEMBL2726851 | 0.87 | MEN1 (0.41) | RECQLCES2GLAHPGDTSHR | |
| SCHEMBL674038 | 0.86 | NAAA (0.41) | RECQLCES2GLAHPGDTSHR | |
| Disodium Laureth Sulfosucccinate SCHEMBL27916855 | 0.86 | NAAA (0.41) | RECQLCES2GLAHPGDTSHR | |
| Cetyl Alcohol SCHEMBL17986422 | 0.85 | CA2 (0.41) | TSHRCA2MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 649 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024781-A | Nanocellulose composite conductive lubricating hydrogel and preparation method thereof | 季华实验室 | 2023-11-10 | — | — | CN | claimed |
| US-20230329232-A1 | Low Viscosity Agricultural Adjuvant for Spraying Syrups and Method of Production | Forquimica Agrociencia Ltda (BR) | 2023-10-19 | — | — | US | claimed |
| EP-4204100-A1 | HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE | L'OREAL (FR) | 2023-07-05 | — | — | EP | claimed |
| CN-116322616-A | Hair lightening compositions providing damage protection and sensory benefits and methods of use | 欧莱雅 | 2023-06-23 | — | — | CN | claimed |
| US-11382844-B2 | Shampoo composition and method of use | CONOPCO, INC. (US) | 2022-07-12 | — | — | US | claimed |
| US-11376209-B2 | Antidandruff composition and method of use | CONOPCO, INC. (US) | 2022-07-05 | — | — | US | claimed |
| US-11260008-B2 | Hair treatment composition | CONOPCO, INC. (US) | 2022-03-01 | — | — | US | claimed |
| US-20210196614-A1 | ANTIDANDRUFF COMPOSITION AND METHOD OF USE | CONOPCO, INC., D/B/A UNILEVER | 2021-07-01 | — | — | US | claimed |
| US-20200281824-A1 | SHAMPOO COMPOSITION AND METHOD OF USE | CONOPCO, INC., D/B/A UNILEVER | 2020-09-10 | — | — | US | claimed |
| EP-3703646-A1 | ANTIDANDRUFF COMPOSITION AND METHOD OF USE | Unilever PLC (GB) | 2020-09-09 | — | — | EP | claimed |
| CN-111295177-A | Shampoo compositions and methods of use | 荷兰联合利华有限公司 | 2020-06-16 | — | — | CN | claimed |
| US-20180147127-A1 | COSMETIC COMPOSITION | OXITENO S.A. INDÚSTRIA E COMÉRCIO (BR) | 2018-05-31 | — | — | US | claimed |
| EP-2504386-B1 | SURFACTANT-POLYMER BLENDS | LUBRIZOL ADVANCED MAT INC (US) | 2017-03-22 | — | — | EP | claimed |
| US-20120213725-A1 | Surfactant-Polymer Blends | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-08-23 | — | — | US | claimed |
| US-20090197784-A1 | Shampoo Compositions Containing a Combination of Cationic Polymers | CONOPCO, INC. D/B/A UNILEVER | 2009-08-06 | — | — | US | claimed |
| EP-1957036-A1 | SHAMPOO COMPOSITIONS CONTAINING A COMBINATION OF CATIONIC POLYMERS | UNILEVER PLC (GB) | 2008-08-20 | — | — | EP | claimed |
| WO-2007147745-A1 | HAND-WASHING PROCESS OF LAUNDRY | CIBA HOLDING INC. (CH) | 2007-12-27 | — | — | WO | claimed |
| WO-2007065537-A1 | SHAMPOO COMPOSITIONS CONTAINING A COMBINATION OF CATIONIC POLYMERS | UNILEVER PLC (GB) | 2007-06-14 | — | — | WO | claimed |
| EP-0271186-B1 | HYDROXYINDOLES AND THEIR USE IN DYEING | REPLIGEN CORPORATION (US) | 1992-12-30 | — | — | EP | claimed |
| EP-0271186-A1 | Hydroxyindoles and their use in dyeing | REPLIGEN CORPORATION (US) | 1988-06-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120213725-A1 | Surfactant-Polymer Blends | SPTAN1, PHOSPHO1, SPTBN1 | CA2 1868/4885THRB 4332/4885CA1 2254/4885 |
| US-20090197784-A1 | Shampoo Compositions Containing a Combination of Cationic Polymers | PLOD3, ALG1, PSAP | CA2 4110/4885THRB 4713/4885CA1 4254/4885 |
| US-11376209-B2 | Antidandruff composition and method of use | ACR, SMURF1, POLR1C | CA2 4073/4885THRB 3585/4885CA1 3298/4885 |
| US-20210196614-A1 | ANTIDANDRUFF COMPOSITION AND METHOD OF USE | ACR, SMURF1, POLR1C | CA2 4073/4885THRB 3585/4885CA1 3298/4885 |
| US-11382844-B2 | Shampoo composition and method of use | CUTA, PCNA, ACR | CA2 3556/4885THRB 3281/4885CA1 3893/4885 |
| US-20200281824-A1 | SHAMPOO COMPOSITION AND METHOD OF USE | CUTA, PCNA, ACR | CA2 3556/4885THRB 3281/4885CA1 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.