Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535393 | 0.89 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9535061 | 0.88 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9534765 | 0.87 | GABRA1 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9534097 | 0.87 | OPRL1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9536735 | 0.84 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9533636 | 0.84 | MAPT (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9537646 | 0.81 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9536200 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL10374406 | 0.79 | HTR1A (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| SCHEMBL9536157 | 0.77 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234173-B1 | PHENOXY-SUBSTITUTED BETA-CARBOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-4945090-A | ANXIOLYTIC AGENTS, ANTICONVULSANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-07-31 | — | — | US | disclosed |