Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578295 | 0.91 | HSP90AA1 (0.56) | HPGDHTTTSHRHSD17B10HSP90AA1 | |
| SCHEMBL3141818 | 0.88 | HTT (0.52) | HPGDHTTTSHRHSD17B10HSP90AA1 | |
| SCHEMBL8472608 | 0.85 | HTT (0.62) | HPGDHTTTSHRHSD17B10CYP3A4 | |
| SCHEMBL14882628 | 0.84 | ALOX15 (0.47) | HPGDHTTTSHRHSD17B10HSP90AA1 | |
| SCHEMBL3892816 | 0.83 | HTT (0.47) | HPGDHTTHSP90AA1CYP3A4MAPT | |
| SCHEMBL1494029 | 0.82 | HTT (0.72) | HPGDHTTHSD17B10CYP3A4MAPT | |
| SCHEMBL4158847 | 0.81 | HTT (0.46) | HPGDHTTTSHRHSP90AA1CYP3A4 | |
| SCHEMBL29495384 | 0.81 | HTT (0.46) | HPGDHTTTSHRHSP90AA1CYP3A4 | |
| SCHEMBL9618645 | 0.81 | HSP90AA1 (0.40) | HPGDHTTTSHRHSD17B10HSP90AA1 | |
| SCHEMBL28803746 | 0.81 | HTT (0.46) | HPGDHTTHSP90AA1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |