Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17071867 | 0.85 | POLB (0.43) | POLBAPEX1HPGDTSHRMAPT | |
| SCHEMBL690412 | 0.83 | POLB (0.46) | POLBAPEX1HPGDTSHRMAPT | |
| SCHEMBL29997409 | 0.83 | POLB (0.46) | POLBAPEX1HPGDTSHRMAPT | |
| SCHEMBL15495179 | 0.83 | ALOX15 (0.47) | POLBHPGDTSHRHSD17B10MAPT | |
| SCHEMBL7069337 | 0.82 | KEAP1 (0.46) | HPGDTSHRHSD17B10MAPTMEN1 | |
| SCHEMBL9533708 | 0.81 | HPGD (0.50) | HSP90AA1POLBHPGDTSHRHSD17B10 | |
| SCHEMBL24445879 | 0.81 | MEN1 (0.42) | POLBHPGDTSHRMAPTMEN1 | |
| SCHEMBL2075295 | 0.80 | KDM4E (0.42) | POLBAPEX1HPGDTSHRMAPT | |
| SCHEMBL9617792 | 0.79 | CA12 (0.44) | POLBAPEX1HPGDTSHRMAPT | |
| SCHEMBL6719734 | 0.79 | NPC1 (0.51) | POLBHPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4356438-A | — | — | None | — | — | JP | disclosed |
| JP-H04356438-A | METHOD FOR PRODUCING ACETOPHENONE COMPOUNDS AND INTERMEDIATE THEREFOR AND METHOD FOR PRODUCING THE SAME | NIPPON NOHYAKU CO LTD | 1992-12-10 | — | — | JP | disclosed |