Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236549 | 0.83 | — | — | |
| SCHEMBL269621 | 0.83 | TDP1 (0.42) | TDP1CYP1A2 | |
| SCHEMBL6624474 | 0.81 | CYP1A2 (0.32) | TDP1CYP1A2 | |
| SCHEMBL109476 | 0.78 | ALDH1A1 (0.42) | TDP1CYP1A2 | |
| SCHEMBL5131814 | 0.78 | — | — | |
| SCHEMBL2558930 | 0.76 | ALDH1A1 (0.46) | TDP1 | |
| SCHEMBL191289 | 0.76 | ALDH1A1 (0.46) | TDP1 | |
| SCHEMBL27650591 | 0.76 | ALDH1A1 (0.46) | TDP1 | |
| SCHEMBL25629838 | 0.76 | CYP1A2 (0.54) | TDP1CYP1A2 | |
| SCHEMBL152231 | 0.76 | ALDH1A1 (0.46) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |