Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533757 | 0.81 | JAK3 (0.31) | CYP1A2TDP1 | |
| SCHEMBL6624831 | 0.79 | RBP4 (0.32) | — | |
| SCHEMBL4880 | 0.79 | — | — | |
| SCHEMBL6039385 | 0.76 | ALDH1A1 (0.46) | CYP1A2TDP1SMN1; SMN2 | |
| SCHEMBL15192539 | 0.76 | — | — | |
| SCHEMBL6624121 | 0.75 | KMT2A (0.31) | KDM4E | |
| SCHEMBL11284764 | 0.74 | ALDH1A1 (0.50) | TDP1SMN1; SMN2 | |
| SCHEMBL19484952 | 0.74 | CYP1A2 (0.59) | CYP1A2TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL3999543 | 0.74 | ALDH1A1 (0.50) | TDP1SMN1; SMN2 | |
| SCHEMBL5858180 | 0.72 | COMT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |