Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902458 | 0.82 | POLB (0.40) | L3MBTL1USP2NPSR1TSHRMEN1 | |
| SCHEMBL7283734 | 0.81 | USP2 (0.47) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL23205826 | 0.76 | USP2 (0.50) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL12125079 | 0.76 | USP2 (0.50) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL16382337 | 0.75 | USP2 (0.48) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL17158348 | 0.74 | ALDH1A1 (0.47) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL9533799 | 0.74 | ALDH1A1 (0.47) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL8328670 | 0.73 | USP2 (0.47) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL18281989 | 0.73 | ALDH1A1 (0.46) | ALDH1A1NPC1L3MBTL1USP2KDM4E | |
| SCHEMBL6836054 | 0.73 | NPC1 (0.58) | ALDH1A1NPC1L3MBTL1KDM4EALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |