Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902462 | 0.82 | HSD17B10 (0.40) | L3MBTL1MEN1KMT2AUSP2NPSR1 | |
| SCHEMBL13178012 | 0.81 | HSD17B10 (0.43) | L3MBTL1MEN1KMT2AUSP2NPSR1 | |
| SCHEMBL7283743 | 0.81 | USP2 (0.47) | ALDH1A1KDM4ENPC1L3MBTL1MEN1 | |
| SCHEMBL27632715 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL296557 | 0.78 | USP2 (0.53) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL23205826 | 0.76 | USP2 (0.50) | ALDH1A1KDM4ENPC1L3MBTL1MEN1 | |
| SCHEMBL12125079 | 0.76 | USP2 (0.50) | ALDH1A1KDM4ENPC1L3MBTL1MEN1 | |
| SCHEMBL16382337 | 0.75 | USP2 (0.48) | ALDH1A1KDM4ENPC1L3MBTL1MEN1 | |
| SCHEMBL7812231 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1L3MBTL1MEN1 | |
| SCHEMBL9533796 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585147-B | MAP4K4 inhibitors | 帝国理工学院创新有限公司 | 2023-12-05 | — | — | CN | disclosed |
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |