Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.72 |
| ▸ | DRD2 | P14416 | 9/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 11/20 | 0.65 |
| ▸ | HTR7 | P34969 | 10/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356978 | 0.95 | ACHE (0.71) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL1545753 | 0.90 | ACHE (0.73) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL3240892 | 0.90 | HTR2A (0.73) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| Fumaric Acid SCHEMBL1545382 | 0.89 | ACHE (0.63) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL1546057 | 0.89 | ACHE (0.68) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL1545611 | 0.87 | ACHE (0.93) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL8795133 | 0.86 | ACHE (0.71) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL604059 | 0.86 | HTR2A (0.73) | ACHEDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL793025 | 0.85 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL1545195 | 0.85 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377528-B1 | Piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA (FR) | 1993-12-08 | — | — | EP | disclosed |
| US-5001134-A | Piperidines, processes of preparation and medications containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1991-03-19 | — | — | US | disclosed |
| EP-0377528-A1 | Piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-07-11 | — | — | EP | disclosed |