Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533168 | 0.92 | GPBAR1 (0.59) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL9535442 | 0.85 | GPBAR1 (0.51) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL9535356 | 0.83 | HSD17B10 (0.52) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL27936754 | 0.82 | HSD17B10 (0.59) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL9533615 | 0.82 | HSD17B10 (0.59) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL5243618 | 0.82 | HSD17B10 (0.59) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL9532664 | 0.82 | HSD17B10 (0.53) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL9534976 | 0.81 | EPAS1 (0.57) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL9534838 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2HPGDRECQLGPBAR1 | |
| SCHEMBL9535763 | 0.74 | KMT2A (0.58) | SMN1; SMN2HPGDGPBAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |