Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534026 | 0.85 | MAPT (0.57) | GPBAR1MAPTKMT2AKDM4EHPGD | |
| SCHEMBL7671051 | 0.81 | PTGS1 (0.49) | GPBAR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9536170 | 0.81 | MAPT (0.52) | GPBAR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9535701 | 0.80 | KMT2A (0.54) | GPBAR1MEN1KMT2APOLBGAA | |
| SCHEMBL5242546 | 0.80 | KMT2A (0.56) | MEN1KMT2APOLBGAATSHR | |
| SCHEMBL9533383 | 0.79 | GPBAR1 (0.51) | GPBAR1MAPTMEN1KMT2APOLB | |
| SCHEMBL27495331 | 0.78 | KMT2A (0.55) | GPBAR1MEN1KMT2APOLBGAA | |
| SCHEMBL9533168 | 0.77 | GPBAR1 (0.59) | GPBAR1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9534238 | 0.74 | POLB (0.45) | GPBAR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL815429 | 0.72 | TAAR1 (0.51) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |