Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533716 | 0.90 | KMT2A (0.51) | EPAS1MAPTGPBAR1SMN1; SMN2HPGD | |
| SCHEMBL9537606 | 0.86 | KDM4E (0.50) | EPAS1MAPTGPBAR1TP53SMN1; SMN2 | |
| SCHEMBL9534026 | 0.81 | MAPT (0.57) | MAPTGPBAR1TP53SMN1; SMN2RECQL | |
| SCHEMBL9533168 | 0.80 | GPBAR1 (0.59) | MAPTGPBAR1TP53SMN1; SMN2RECQL | |
| SCHEMBL9535356 | 0.76 | HSD17B10 (0.52) | MAPTGPBAR1TP53SMN1; SMN2RECQL | |
| SCHEMBL5243618 | 0.75 | HSD17B10 (0.59) | MAPTGPBAR1TP53SMN1; SMN2RECQL | |
| SCHEMBL27936754 | 0.75 | HSD17B10 (0.59) | MAPTGPBAR1TP53SMN1; SMN2RECQL | |
| SCHEMBL9533615 | 0.75 | HSD17B10 (0.59) | EPAS1MAPTGPBAR1TP53SMN1; SMN2 | |
| SCHEMBL9532664 | 0.75 | HSD17B10 (0.53) | MAPTGPBAR1TP53SMN1; SMN2RECQL | |
| SCHEMBL30395450 | 0.73 | EPAS1 (1.00) | EPAS1MAPTGPBAR1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |