Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534048 | 1.00 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL9534900 | 0.85 | SMN1; SMN2 (0.45) | CYSLTR2CYSLTR1SMN1; SMN2 | |
| SCHEMBL9533128 | 0.85 | SMN1; SMN2 (0.45) | CYSLTR2CYSLTR1SMN1; SMN2 | |
| SCHEMBL9537800 | 0.79 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL9505459 | 0.76 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9539184 | 0.76 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL9533367 | 0.76 | SMN1; SMN2 (0.42) | CYSLTR2CYSLTR1SMN1; SMN2 | |
| SCHEMBL9560172 | 0.74 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1MAPTRXFP1SMN1; SMN2 | |
| Pobilukast SCHEMBL29473536 | 0.74 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL6437479 | 0.74 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | claimed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | claimed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | claimed |