Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495622 | 0.76 | PTGER2 (0.44) | DNTTPPARGPPARDPPARATRPA1 | |
| SCHEMBL9497680 | 0.74 | PTGER2 (0.46) | DNTTPPARGPPARDPPARATRPA1 | |
| SCHEMBL16287745 | 0.73 | HCAR2 (0.40) | CNR1CNR2KEAP1NFE2L2HCAR2 | |
| SCHEMBL31681514 | 0.72 | HCAR2 (0.55) | PPARGPPARACNR1CNR2KEAP1 | |
| SCHEMBL8848785 | 0.71 | PPARG (0.50) | DNTTPPARGPPARDPPARATRPA1 | |
| SCHEMBL9535804 | 0.70 | KEAP1 (0.32) | CNR1CNR2KEAP1NFE2L2HCAR2 | |
| SCHEMBL10385891 | 0.70 | PPARG (0.52) | DNTTPPARGPPARDPPARATRPA1 | |
| SCHEMBL10617209 | 0.70 | PPARG (0.40) | DNTTPPARGPPARDPPARATRPA1 | |
| SCHEMBL10629076 | 0.70 | PPARG (0.52) | DNTTPPARGPPARDPPARATRPA1 | |
| SCHEMBL10631459 | 0.69 | PPARG (0.44) | DNTTPPARGPPARDPPARATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362816-B1 | Cyclopenteneheptanoic acid derivatives and method of preparation thereof | SEARLE & CO (US) | 1993-11-18 | — | — | EP | disclosed |
| US-4952710-A | STARTING MATERIAL FOR OPTICALLY ACTIVE PROSTAGLANDINS | G. D. SEARLE & CO. (US) | 1990-08-28 | — | — | US | disclosed |