Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.50 |
| ▸ | USP7 | Q93009 | 2/20 | 0.48 |
| ▸ | USP10 | Q14694 | 1/20 | 0.48 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534810 | 0.85 | USP7 (0.51) | USP7USP10USP47KMT2AMEN1 | |
| SCHEMBL9538420 | 0.83 | USP7 (0.60) | USP7USP10USP47KMT2AMEN1 | |
| SCHEMBL4001925 | 0.82 | MAPT (0.52) | GSTP1GSTM2KMT2AMEN1MAPT | |
| SCHEMBL9536466 | 0.82 | USP7 (0.48) | USP7USP10USP47KMT2AMEN1 | |
| SCHEMBL9537312 | 0.82 | USP7 (0.52) | GSTP1GSTM2USP7USP10USP47 | |
| SCHEMBL9538516 | 0.81 | MAPT (0.45) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL9535526 | 0.81 | USP7 (0.51) | GSTP1GSTM2USP7USP10USP47 | |
| SCHEMBL9538237 | 0.81 | USP7 (0.54) | USP7USP10USP47KMT2AMEN1 | |
| SCHEMBL9537206 | 0.81 | USP7 (0.51) | USP7USP10USP47KMT2AMEN1 | |
| SCHEMBL9539302 | 0.81 | ALDH1A1 (0.53) | GSTP1GSTM2USP7USP10USP47 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |