Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.52 |
| ▸ | USP10 | Q14694 | 1/20 | 0.52 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.43 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538420 | 0.88 | USP7 (0.60) | USP7USP10USP47ATMTDP1 | |
| SCHEMBL9535526 | 0.88 | USP7 (0.51) | USP7USP10USP47ATMTDP1 | |
| SCHEMBL9538237 | 0.88 | USP7 (0.54) | USP7USP10USP47CASP6ATM | |
| SCHEMBL9539302 | 0.85 | ALDH1A1 (0.53) | USP7USP10USP47ATMTDP1 | |
| SCHEMBL9537206 | 0.85 | USP7 (0.51) | USP7USP10USP47ATMTDP1 | |
| SCHEMBL9534810 | 0.85 | USP7 (0.51) | USP7USP10USP47ATMTDP1 | |
| SCHEMBL18376634 | 0.84 | POLB (0.57) | CASP6APEX1TSHRALDH1A1LMNA | |
| SCHEMBL9536532 | 0.84 | KMT2A (0.52) | USP7USP10USP47TDP1TSHR | |
| SCHEMBL9536970 | 0.82 | HTT (0.56) | USP7USP10USP47ATMTDP1 | |
| SCHEMBL9534191 | 0.82 | GSTP1 (0.50) | USP7USP10USP47ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |