Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802596 | 0.69 | — | — | |
| SCHEMBL21768538 | 0.69 | TSHR (0.53) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL6997281 | 0.69 | TSHR (0.53) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL9811103 | 0.66 | POLB (0.63) | SMN1; SMN2TSHRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL56403 | 0.66 | TSHR (0.63) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| Benzene SCHEMBL28110883 | 0.65 | PKM (0.59) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL2053300 | 0.65 | TSHR (0.50) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL10454012 | 0.65 | TSHR (0.49) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL29207431 | 0.64 | TSHR (0.61) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL28545578 | 0.64 | TSHR (0.61) | PKMSMN1; SMN2TSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252474-B1 | HYDRAZINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |