Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326877 | 0.88 | GAA (0.49) | GAAKDM4ENAAAALDH1A1DRD3 | |
| SCHEMBL6970411 | 0.83 | SLC18A3 (0.47) | GAAALDH1A1DRD3MEN1KMT2A | |
| SCHEMBL10174987 | 0.82 | ALDH1A1 (0.48) | GAAKDM4ENAAAALDH1A1DRD3 | |
| SCHEMBL12014416 | 0.80 | SIGMAR1 (0.48) | GAAKDM4ENAAAALDH1A1MEN1 | |
| SCHEMBL64187 | 0.79 | KDM4E (0.50) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27376870 | 0.77 | KDM4E (0.41) | GAAKDM4ENAAAALDH1A1DRD3 | |
| SCHEMBL6968733 | 0.76 | MEN1 (0.45) | GAAKDM4ENAAAALDH1A1DRD3 | |
| SCHEMBL4184236 | 0.76 | ALDH1A1 (0.56) | GAAKDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6968727 | 0.76 | GAA (0.42) | GAAKDM4ENAAAALDH1A1DRD3 | |
| SCHEMBL27394006 | 0.75 | ALDH1A1 (0.50) | GAAKDM4ENAAAALDH1A1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |