Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1452610 | 0.82 | HDAC3 (0.43) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| SCHEMBL978014 | 0.78 | TSHR (0.48) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| SCHEMBL46757 | 0.71 | HTR2A (0.63) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| SCHEMBL62723 | 0.71 | TSHR (0.67) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| SCHEMBL9619728 | 0.70 | TSHR (0.41) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Ammonia Solution, Strong SCHEMBL266843 | 0.69 | HTR2A (0.61) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| SCHEMBL13063690 | 0.69 | TSHR (0.48) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Methylamine SCHEMBL27581718 | 0.69 | TSHR (0.65) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Methyl Alcohol SCHEMBL9419583 | 0.69 | TSHR (0.58) | TSHRMAPK1HTR2AHTR2BHTR2C | |
| Fluoride SCHEMBL30661872 | 0.69 | TSHR (0.64) | TSHRMAPK1HTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559843-A1 | SUBSTITUTED N-HETEROBICYCLIC HERBICIDES. | DU PONT (US) | 1993-09-15 | — | — | EP | disclosed |