Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532760 | 0.91 | EGLN1 (0.32) | — | |
| SCHEMBL9536515 | 0.86 | LMNA (0.32) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL6605949 | 0.84 | LMNA (0.41) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9534520 | 0.83 | LMNA (0.30) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9094644 | 0.81 | LMNA (0.39) | LMNA | |
| SCHEMBL9533039 | 0.81 | DPP4 (0.40) | LMNACYP2C9 | |
| SCHEMBL6603303 | 0.81 | LMNA (0.44) | LMNA | |
| SCHEMBL9097578 | 0.80 | MAP2K1 (0.37) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9096358 | 0.78 | MAP2K2 (0.38) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL7234823 | 0.78 | KMT2A (0.47) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379413-B1 | 1,8-Benzonaphthyridine derivatives, their production and compositions containing them | BELLON LABOR SA ROGER (FR) | 1993-12-22 | — | — | EP | claimed |