Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534484 | 0.91 | LMNA (0.31) | — | |
| SCHEMBL7230355 | 0.85 | LMNA (0.39) | EGLN1 | |
| SCHEMBL9532522 | 0.80 | BAZ2B (0.48) | — | |
| SCHEMBL9534520 | 0.80 | LMNA (0.30) | — | |
| SCHEMBL6603303 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL9536515 | 0.77 | LMNA (0.32) | — | |
| SCHEMBL6605949 | 0.75 | LMNA (0.41) | — | |
| SCHEMBL7235145 | 0.74 | CYP2C9 (0.37) | EGLN1 | |
| SCHEMBL9533039 | 0.73 | DPP4 (0.40) | — | |
| SCHEMBL9775979 | 0.73 | TOP2A (0.37) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379413-B1 | 1,8-Benzonaphthyridine derivatives, their production and compositions containing them | BELLON LABOR SA ROGER (FR) | 1993-12-22 | — | — | EP | claimed |