Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22571124 | 0.82 | ALDH1A1 (0.56) | CHRNA7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22571125 | 0.82 | ALDH1A1 (0.56) | CHRNA7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9531239 | 0.79 | SMN1; SMN2 (0.46) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9530731 | 0.77 | TSHR (0.33) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7099567 | 0.77 | KMT2A (0.43) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24223726 | 0.76 | ALDH1A1 (0.49) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9774300 | 0.76 | KMT2A (0.42) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22571091 | 0.74 | GAA (0.46) | CHRNA7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22571089 | 0.74 | GAA (0.46) | CHRNA7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24223605 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-B1 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | LILLY CO ELI (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4734498-A | 3β-succinimidoazetidinones as chiral intermediates | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0252744-A2 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |