Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534650 | 0.87 | MCL1 (0.32) | MCL1 | |
| SCHEMBL9534655 | 0.78 | HMGCR (0.40) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL5598279 | 0.72 | ALDH1A1 (0.46) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL5598275 | 0.72 | ALDH1A1 (0.46) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL1336381 | 0.71 | DPP4 (0.36) | — | |
| SCHEMBL30794442 | 0.69 | PIK3CD (0.39) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| Bicarbonate SCHEMBL11385004 | 0.69 | DPP4 (0.35) | — | |
| SCHEMBL8508470 | 0.68 | DPP4 (0.33) | CHRM1ADRA1A | |
| SCHEMBL11120681 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL19391257 | 0.67 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178106-B1 | ENZYMATIC PROCESS | NOVO NORDISK A/S (DK) | 1993-03-31 | — | — | EP | disclosed |
| EP-0178106-A2 | Enzymatic process | NOVO NORDISK A/S (DK) | 1986-04-16 | — | — | EP | disclosed |