Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534650 | 0.87 | MCL1 (0.32) | — | |
| SCHEMBL9534645 | 0.78 | KDM4E (0.31) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL1898374 | 0.73 | DPP4 (0.39) | — | |
| SCHEMBL8409023 | 0.71 | CA1 (0.36) | — | |
| SCHEMBL6479538 | 0.67 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL22965333 | 0.66 | HMGCR (0.55) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL6130132 | 0.66 | ALDH1A1 (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL6130129 | 0.66 | ALDH1A1 (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL20134685 | 0.65 | HMGCR (0.52) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL5478252 | 0.64 | ADRA1A (0.46) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178106-B1 | ENZYMATIC PROCESS | NOVO NORDISK A/S (DK) | 1993-03-31 | — | — | EP | disclosed |
| EP-0178106-A2 | Enzymatic process | NOVO NORDISK A/S (DK) | 1986-04-16 | — | — | EP | disclosed |