Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005491 | 0.83 | SLC22A12 (0.47) | MAP2K1PARP14SLC22A12 | |
| SCHEMBL29467983 | 0.80 | ACLY (0.52) | MAP2K1PARP14SLC22A12 | |
| SCHEMBL10208423 | 0.80 | ACLY (0.52) | MAP2K1PARP14SLC22A12 | |
| SCHEMBL9655254 | 0.80 | PTGS2 (0.58) | PTGS2TBXA2RSLC22A12 | |
| SCHEMBL9535031 | 0.79 | PTGS2 (0.55) | PTGS2PARP14TBXA2RPTGES2SLC22A12 | |
| SCHEMBL9656863 | 0.79 | PTGS2 (0.57) | PTGS2TBXA2RSLC22A12 | |
| SCHEMBL9656869 | 0.79 | PTGS2 (0.57) | PTGS2TBXA2RSLC22A12KMT2A | |
| SCHEMBL10626704 | 0.78 | PTGS2 (0.56) | PTGS2SOS1PLA2G7LMNAPTGS1 | |
| SCHEMBL9537258 | 0.77 | TBXA2R (0.39) | PTGS2PARP14PLA2G7TBXA2RPTGES2 | |
| SCHEMBL9535652 | 0.76 | PTGS2 (0.54) | PTGS2SOS1PLA2G7ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |