⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905823 | 0.73 | KDM4E (0.32) | — | |
| SCHEMBL3958827 | 0.73 | — | — | |
| SCHEMBL10681446 | 0.72 | — | — | |
| SCHEMBL11805074 | 0.72 | — | — | |
| SCHEMBL9141910 | 0.70 | — | — | |
| SCHEMBL8006773 | 0.67 | — | — | |
| SCHEMBL3908846 | 0.66 | — | — | |
| SCHEMBL5722117 | 0.66 | GSR (0.31) | — | |
| SCHEMBL7551288 | 0.66 | — | — | |
| SCHEMBL3953992 | 0.66 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1023318-C | Process for preparing 1-hydroxyalkyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-29 | — | — | CN | claimed |
| CN-1023220-C | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | claimed |
| EP-0325513-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-2-METHYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1993-04-07 | — | — | EP | claimed |
| EP-0324691-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-12-27 | — | — | EP | claimed |
| CN-1055536-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC RORER SA (FR) | 1991-10-23 | — | — | CN | claimed |
| CN-1035288-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | claimed |
| CN-1035289-A | The preparation method of 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | claimed |
| CN-1023318-C | Process for preparing 1-hydroxyalkyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-29 | — | — | CN | disclosed |
| CN-1023220-C | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | disclosed |
| CN-1016782-B | PROCESS FOR PREPARING 1-ETHYLOL-2-METHYL-5-NITROIMIDAZOLE | RHONE POULENC SANTE (FR) | 1992-05-27 | — | — | CN | disclosed |
| EP-0439556-A4 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | — | 1991-10-30 | — | — | EP | disclosed |
| CN-1055536-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC RORER SA (FR) | 1991-10-23 | — | — | CN | disclosed |
| CN-1035289-A | The preparation method of 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035288-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035288-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035289-A | The preparation method of 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035111-A | Hydroxyalkyl agent preparation method, gained new preparation and application thereof like this | RHONE POULENC SANTE (FR) | 1989-08-30 | — | — | CN | disclosed |