Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869141 | 0.75 | SLC6A4 (0.38) | SLC6A3SLC6A4SLC6A2HSD11B1KDM1A | |
| SCHEMBL2662444 | 0.68 | SLC6A4 (0.41) | SLC6A3SLC6A4SLC6A2MAP3K14TP53 | |
| SCHEMBL17186750 | 0.66 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2MAP3K14HSD11B1 | |
| SCHEMBL21291315 | 0.66 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2HSD11B1HSD11B2 | |
| SCHEMBL18769595 | 0.66 | SLC6A4 (0.54) | SLC6A3SLC6A4SLC6A2HSD11B1HSD11B2 | |
| SCHEMBL2171978 | 0.66 | SLC6A4 (0.42) | SLC6A3SLC6A4SLC6A2TP53MEN1 | |
| SCHEMBL17186865 | 0.66 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2MAP3K14HSD11B1 | |
| SCHEMBL26385838 | 0.66 | SLC6A4 (0.50) | SLC6A3SLC6A4SLC6A2HSD11B1HSD11B2 | |
| SCHEMBL12134100 | 0.66 | SLC6A4 (0.42) | SLC6A3SLC6A4MAP3K14TP53ATM | |
| SCHEMBL17186741 | 0.66 | MAP3K14 (0.43) | SLC6A3SLC6A4SLC6A2MAP3K14P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246982-B1 | TRIAZOLE OR IMIDAZOLE AND TETRAHYDROFURAN COMPOUNDS, THEIR USE AS FUNGICIDES AND PREPARATION PROCESSES | RHONE-POULENC AGROCHIMIE (FR) | 1993-02-03 | — | — | EP | disclosed |
| EP-0246982-A2 | Triazole or imidazole and tetrahydrofuran compounds, their use as fungicides and preparation processes | RHONE-POULENC AGROCHIMIE (FR) | 1987-11-25 | — | — | EP | disclosed |