Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304756 | 0.77 | — | — | |
| SCHEMBL9534713 | 0.75 | SLC6A3 (0.44) | SLC6A4SLC6A3SLC6A2HSD11B1KDM1A | |
| SCHEMBL7385793 | 0.69 | OPRM1 (0.41) | SLC6A4SLC6A3ALDH1A1DRD2SLC6A2 | |
| SCHEMBL2108 | 0.69 | SLC6A4 (0.44) | SLC6A4SLC6A3DRD2SLC6A2HDAC4 | |
| SCHEMBL8116292 | 0.69 | SLC6A3 (0.48) | SLC6A4SLC6A3DRD2SLC6A2HDAC4 | |
| SCHEMBL2082383 | 0.68 | ALDH1A1 (0.48) | SLC6A4SLC6A3ALDH1A1SLC6A2MAOA | |
| SCHEMBL7385753 | 0.68 | ITGB1 (0.44) | ALDH1A1HDAC4HSD11B1 | |
| SCHEMBL5430518 | 0.68 | SLC6A4 (0.41) | SLC6A4SLC6A3ALDH1A1DRD2SLC6A2 | |
| SCHEMBL3174097 | 0.68 | DRD2 (0.43) | SLC6A4SLC6A3DRD2SLC6A2HDAC4 | |
| SCHEMBL29259636 | 0.67 | SLC6A3 (0.52) | SLC6A4SLC6A3DRD2SLC6A2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |