Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.63 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381309 | 0.89 | MAOB (0.60) | MAOBCD274PDCD1KDM4EPOLB | |
| SCHEMBL10381326 | 0.89 | MAOB (0.60) | MAOBCD274PDCD1KDM4EPOLB | |
| SCHEMBL9533962 | 0.86 | MAOB (0.62) | MAOBCD274PDCD1KDM4ETDP1 | |
| SCHEMBL9531614 | 0.86 | MAOB (0.49) | MAOBCD274KDM4EPOLBCASP6 | |
| SCHEMBL9536771 | 0.85 | MAOB (0.61) | MAOBCD274PDCD1KDM4EPOLB | |
| SCHEMBL10382659 | 0.83 | MAOB (0.64) | MAOBKDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL9536658 | 0.82 | MAOB (0.64) | MAOBCD274KDM4ETDP1L3MBTL1 | |
| SCHEMBL9532937 | 0.81 | MAOB (0.62) | MAOBCD274PDCD1KDM4EPOLB | |
| SCHEMBL9534068 | 0.81 | MAOB (0.62) | MAOBKDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL9533087 | 0.81 | MAOB (0.57) | MAOBKDM4EPOLBCASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| WO-1990001481-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1990-02-22 | — | — | WO | disclosed |