Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672053 | 1.00 | SOAT1 (0.43) | SOAT1GSK3BBACE1AVPR1AMEN1 | |
| SCHEMBL9534753 | 1.00 | SOAT1 (0.43) | SOAT1GSK3BBACE1AVPR1AMEN1 | |
| SCHEMBL13778892 | 0.82 | SOAT1 (0.46) | SOAT1MEN1KMT2ATSHRMAPT | |
| SCHEMBL21944494 | 0.81 | TRPA1 (0.41) | SOAT1MEN1KMT2ATSHRMAOB | |
| SCHEMBL18716240 | 0.81 | TRPA1 (0.41) | SOAT1MEN1KMT2ATSHRMAOB | |
| SCHEMBL17303910 | 0.81 | TRPA1 (0.41) | SOAT1MEN1KMT2ATSHRMAOB | |
| SCHEMBL10546219 | 0.80 | RAB9A (0.49) | SOAT1AVPR1AMEN1KMT2ATRPA1 | |
| SCHEMBL10513571 | 0.80 | RAB9A (0.49) | SOAT1AVPR1AMEN1KMT2ATRPA1 | |
| SCHEMBL10546195 | 0.80 | RAB9A (0.49) | SOAT1AVPR1AMEN1KMT2ATRPA1 | |
| SCHEMBL10513582 | 0.80 | RAB9A (0.49) | SOAT1AVPR1AMEN1KMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-B1 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | LILLY CO ELI (US) | 1993-12-15 | — | — | EP | disclosed |