Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535280 | 0.87 | KDM4E (0.63) | HSD17B10KDM4EALDH1A1HPGDDHODH | |
| SCHEMBL9535645 | 0.86 | KDM4E (0.48) | HSD17B10KDM4EALDH1A1HPGDDHODH | |
| SCHEMBL9535317 | 0.81 | HSD17B10 (0.44) | HSD17B10KMT2AKDM4EDYRK1ADYRK2 | |
| SCHEMBL9534760 | 0.81 | DYRK1A (0.46) | HSD17B10KMT2AKDM4EDYRK1ADYRK2 | |
| SCHEMBL9870239 | 0.74 | KDM4E (0.43) | HSD17B10KMT2AKDM4EDYRK1ADYRK2 | |
| SCHEMBL11467433 | 0.73 | KDM4E (0.54) | HSD17B10KMT2AKDM4EDYRK1ADYRK2 | |
| SCHEMBL8939337 | 0.72 | DHODH (0.42) | HSD17B10KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9468353 | 0.72 | KDM4E (0.70) | HSD17B10KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9534772 | 0.72 | KDM4E (0.56) | HSD17B10KMT2AKDM4EDYRK1ADYRK2 | |
| SCHEMBL10407651 | 0.70 | DHODH (0.52) | KMT2AALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353902-B1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-05 | — | — | EP | claimed |
| EP-0353902-A1 | Substituted phenyltriazolopyrimidine herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | claimed |
| EP-0353902-B1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5127936-A | Substituted phenyltriazolopyrimidine herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1990012012-A1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0353902-A1 | Substituted phenyltriazolopyrimidine herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |