Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534839 | 0.86 | HSD17B10 (0.49) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL9535280 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9538733 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9538048 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9536061 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL20539885 | 0.77 | DHODH (0.64) | HSD17B10DHODH | |
| SCHEMBL1681588 | 0.75 | DHODH (0.52) | ALDH1A1DHODH | |
| SCHEMBL8939337 | 0.71 | DHODH (0.42) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL11898278 | 0.70 | DHODH (0.74) | ALDH1A1HSD17B10DHODHSMN1; SMN2 | |
| SCHEMBL9537071 | 0.70 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353902-B1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-05 | — | — | EP | claimed |
| EP-0440659-A1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-14 | — | — | EP | claimed |
| WO-1990012012-A1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-18 | — | — | WO | claimed |
| WO-1990001030-A1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-08 | — | — | WO | claimed |
| EP-0353902-A1 | Substituted phenyltriazolopyrimidine herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | claimed |
| EP-0353902-B1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5127936-A | Substituted phenyltriazolopyrimidine herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1990012012-A1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0353902-A1 | Substituted phenyltriazolopyrimidine herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |