Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312583 | 0.80 | KMT2A (0.36) | ALDH1A1MEN1KMT2APOLBGABRA1 | |
| SCHEMBL13168023 | 0.76 | GABRA1 (0.33) | ALDH1A1MEN1KMT2APOLBGABRA1 | |
| SCHEMBL16480192 | 0.74 | GABRA1 (0.34) | ALDH1A1MEN1KMT2APOLBGABRA1 | |
| SCHEMBL15579628 | 0.74 | ALDH1A1 (0.34) | ALDH1A1CDK5CDK5R1MEN1KMT2A | |
| SCHEMBL14411069 | 0.73 | GABRA1 (0.35) | ALDH1A1MEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL13357367 | 0.73 | GABRA1 (0.33) | ALDH1A1MEN1KMT2APOLBGABRA1 | |
| SCHEMBL13817854 | 0.72 | HTR2A (0.38) | MEN1KMT2A | |
| SCHEMBL13527448 | 0.71 | CDK5 (0.32) | CDK5CDK5R1 | |
| SCHEMBL13527231 | 0.71 | GABRA1 (0.30) | CDK5CDK5R1GABRA1GABRG2GABRB3 | |
| SCHEMBL14411023 | 0.71 | GABRA1 (0.35) | ALDH1A1MEN1KMT2AGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5142065-A | Intermediates for herbicides, fungicides, miticides and insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |