SCHEMBL9534875

SCHEMBL9534875

C#CCn1c(=O)sc2cc(F)c(-n3nc4c(n3)CCCC4)cc21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPOX P50336 2/20 0.34
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9535332 0.84 SHMT2 (0.40) ALDH1A1LMNAALOX15SMN1; SMN2
SCHEMBL9369024 0.82 PPOX (0.34) PPOX
SCHEMBL9535743 0.81 PPOX (0.30) PPOX
SCHEMBL10365372 0.81 GRM7 (0.37)
SCHEMBL9837325 0.77 TMEM97 (0.36) PPOX
SCHEMBL9535058 0.77 CNR2 (0.35)
SCHEMBL8362026 0.74 POLB (0.34) PPOXALDH1A1SMN1; SMN2PKM
SCHEMBL9711627 0.74 PPOX (0.34) PPOXALDH1A1SMN1; SMN2
SCHEMBL9781614 0.74 TMEM97 (0.31) PPOX
SCHEMBL9837580 0.73 TMEM97 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274066-B1 BENZOTHIAZOLONES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP claimed