Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537606 | 0.94 | KDM4E (0.50) | KMT2AEPAS1GLAALDH1A1LMNA | |
| SCHEMBL9534976 | 0.90 | EPAS1 (0.57) | KMT2AEPAS1LMNAGAAMAPT | |
| SCHEMBL9535763 | 0.76 | KMT2A (0.58) | KMT2APTGS2GLAALDH1A1LMNA | |
| SCHEMBL5242545 | 0.76 | ALDH1A1 (0.60) | KMT2APTGS2GLAPKMTSHR | |
| SCHEMBL9533922 | 0.76 | TSHR (0.59) | KMT2APTGS2GLAPKMTSHR | |
| SCHEMBL9537421 | 0.75 | TSHR (0.53) | PTGS2GLAPKMTSHRALDH1A1 | |
| SCHEMBL30116329 | 0.74 | PRSS1 (0.55) | LMNAMAPTKDM4ENPSR1 | |
| SCHEMBL11904756 | 0.74 | PRSS1 (0.55) | LMNAMAPTKDM4ENPSR1 | |
| SCHEMBL9535614 | 0.73 | TSHR (0.53) | KMT2APTGS2GLAPKMTSHR | |
| SCHEMBL27936779 | 0.72 | GPBAR1 (0.55) | KMT2AEPAS1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0556225-A1 | SUBSTITUTED PYRIDO 2,3-d]PYRIMIDIN-2,4(1H,3H)-DIONES | BASF Aktiengesellschaft (DE) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992008719-A1 | SUBSTITUTED PYRIDO[2,3-d]PYRIMIDIN-2,4(1H,3H)-DIONES | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-29 | — | — | WO | disclosed |