Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532203 | 0.86 | KDM4E (0.65) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL10668697 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL9533630 | 0.83 | KDM4E (0.62) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| Bromide SCHEMBL11085283 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL9534712 | 0.81 | KDM4E (0.59) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL9532680 | 0.81 | KDM4E (0.63) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL9770613 | 0.80 | KDM4E (0.61) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL9538352 | 0.78 | KDM4E (0.55) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL10978164 | 0.77 | KDM4E (1.00) | ALDH1A1HPGDKDM4EHSD17B10GLA | |
| SCHEMBL9534383 | 0.71 | TDP1 (0.50) | ALDH1A1KDM4EHSD17B10SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |