Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.49 |
| ▸ | REN | P00797 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270681 | 0.86 | CTRB1 (0.58) | MTNR1AMTNR1BCTRB1RENCTSS | |
| SCHEMBL7443833 | 0.82 | BACE1 (0.44) | MTNR1AMTNR1B | |
| SCHEMBL19954666 | 0.82 | CTRB1 (0.54) | CTRB1RENCTSSCTSKLMNA | |
| SCHEMBL9231447 | 0.79 | KLK5 (0.58) | CTSSCTSK | |
| SCHEMBL9238345 | 0.79 | KLK5 (0.58) | CTSSCTSK | |
| SCHEMBL9237407 | 0.79 | KLK5 (0.58) | CTSSCTSK | |
| SCHEMBL14866005 | 0.79 | CTRB1 (0.54) | CTRB1CTSSCTSKLMNAPAM | |
| SCHEMBL14865952 | 0.78 | CTRB1 (0.53) | CTRB1CTSSCTSKLMNAPAM | |
| SCHEMBL14570232 | 0.77 | CTRB1 (0.55) | MTNR1AMTNR1BCTRB1CTSSCTSK | |
| SCHEMBL7434134 | 0.77 | CTRB1 (0.55) | MTNR1AMTNR1BCTRB1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |