SCHEMBL9535153

SCHEMBL9535153

O=C(OCc1ccccc1)C(=O)OCC1CCCO1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
MGLL Q99685 2/20 0.53
HTT P42858 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28236593 0.85 CYP1A2 (0.47) CYP1A2MGLLHTTALDH1A1MAPT
SCHEMBL28206027 0.82 CYP1A2 (0.46) CYP1A2MGLLHTTALDH1A1MAPT
SCHEMBL20269268 0.82 MGLL (0.64) MGLLALDH1A1
SCHEMBL9537976 0.82 CYP1A2 (0.55) CYP1A2MGLLALDH1A1
SCHEMBL26642990 0.81 CYP1A2 (0.46) CYP1A2HTTALDH1A1
SCHEMBL27762023 0.80 CYP1A2 (0.56) CYP1A2ALDH1A1
SCHEMBL5660476 0.79 LMNA (0.50) CYP1A2
SCHEMBL21283683 0.79 LMNA (0.50) CYP1A2
SCHEMBL29051134 0.79 MEN1 (0.58) ALDH1A1MAPT
SCHEMBL23394177 0.78 HPGD (0.57) MGLLHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539372-A1 THERAPEUTIC AGENTS The Boots Company PLC (GB) 1993-05-05 EP disclosed