Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181177 | 0.84 | HTR7 (0.51) | HTR7HRH2HRH1 | |
| SCHEMBL9352867 | 0.80 | CARM1 (0.54) | CARM1PRMT6BCHEFFAR4HRH2 | |
| SCHEMBL4024133 | 0.80 | BCHE (0.62) | CARM1PRMT6BCHEHTR4 | |
| Hydrochloric Acid SCHEMBL9353143 | 0.78 | CARM1 (0.54) | CARM1PRMT6BCHEHTR7FFAR4 | |
| SCHEMBL9356788 | 0.76 | CARM1 (0.51) | CARM1PRMT6BCHEFFAR4HRH1 | |
| SCHEMBL9531532 | 0.76 | BCHE (0.65) | BCHEHRH2HRH1CHRM3 | |
| SCHEMBL7949172 | 0.75 | DRD2 (0.61) | — | |
| SCHEMBL10435992 | 0.75 | CARM1 (0.46) | CARM1PRMT6BCHEHTR7FFAR4 | |
| SCHEMBL9352689 | 0.74 | CARM1 (0.57) | CARM1PRMT6BCHEFFAR4CHRM3 | |
| SCHEMBL21206426 | 0.74 | BCHE (0.54) | CARM1PRMT6BCHEHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335586-B1 | PIPERIDINE & PIPERAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| EP-0335586-A1 | Piperidine & piperazine derivatives, process for preparing the same and pharmaceutical compositions containing the same | UBE INDUSTRIES, LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |