Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127479 | 0.77 | EGFR (0.50) | EGFRPIK3CDPIK3CA | |
| SCHEMBL28003243 | 0.74 | EGFR (0.48) | EGFRPIK3CDPIK3CA | |
| SCHEMBL30466588 | 0.73 | DYRK1A (0.41) | EGFRPIK3CDPIK3CA | |
| SCHEMBL392075 | 0.73 | EGFR (0.35) | EGFRPIK3CDPIK3CA | |
| SCHEMBL5763741 | 0.73 | EGFR (0.53) | EGFRPIK3CDPIK3CA | |
| SCHEMBL12909563 | 0.73 | CYP1A2 (0.42) | EGFRPIK3CDPIK3CA | |
| SCHEMBL3970860 | 0.73 | MAP4K4 (0.38) | EGFRPIK3CDPIK3CA | |
| SCHEMBL21936740 | 0.70 | EGFR (0.60) | EGFRPIK3CDPIK3CA | |
| SCHEMBL22778437 | 0.68 | DGAT1 (0.39) | EGFRPIK3CDPIK3CA | |
| SCHEMBL10077307 | 0.68 | EGFR (0.33) | EGFRPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312794-B1 | THIAZETIDINE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-05-19 | — | — | EP | disclosed |
| EP-0312794-A1 | Thiazetidine derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-04-26 | — | — | EP | disclosed |