Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CCR4 | P51679 | 3/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537849 | 0.91 | TSHR (0.42) | TSHRSMN1; SMN2CCR4 | |
| SCHEMBL909656 | 0.88 | TSHR (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL8113170 | 0.87 | TSHR (0.39) | TSHRCCR4 | |
| SCHEMBL7850649 | 0.83 | TSHR (0.41) | TSHRSMN1; SMN2CCR4NUDT1 | |
| SCHEMBL8890841 | 0.81 | TSHR (0.35) | TSHRSMN1; SMN2CCR4 | |
| SCHEMBL7841686 | 0.81 | TSHR (0.40) | TSHRCCR4 | |
| SCHEMBL8356685 | 0.81 | TSHR (0.46) | TSHRSMN1; SMN2CCR4 | |
| SCHEMBL7850325 | 0.81 | TSHR (0.43) | TSHRCCR4 | |
| SCHEMBL10687843 | 0.80 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2CCR4 | |
| SCHEMBL8902874 | 0.80 | SMN1; SMN2 (0.41) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | disclosed |