Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910148 | 0.91 | TSHR (0.36) | TSHRFFAR4ALDH1A1LMNAHPGD | |
| SCHEMBL9534360 | 0.91 | TSHR (0.36) | TSHRFFAR4ALDH1A1LMNAHPGD | |
| SCHEMBL8335333 | 0.91 | TSHR (0.32) | TSHRFFAR4ALDH1A1LMNAPTGS2 | |
| SCHEMBL9535324 | 0.88 | TSHR (0.42) | TSHRSMN1; SMN2 | |
| SCHEMBL7850191 | 0.85 | FFAR4 (0.40) | TSHRFFAR4ALDH1A1SMN1; SMN2PTGS2 | |
| Metosulam SCHEMBL23302655 | 0.83 | TSHR (0.41) | TSHRFFAR4ALDH1A1LMNAHPGD | |
| Metosulam SCHEMBL29516826 | 0.83 | TSHR (0.41) | TSHRFFAR4ALDH1A1LMNAHPGD | |
| Metosulam SCHEMBL55076 | 0.83 | TSHR (0.41) | TSHRFFAR4ALDH1A1LMNAHPGD | |
| SCHEMBL7074184 | 0.81 | TSHR (0.34) | TSHRFFAR4SMN1; SMN2 | |
| SCHEMBL8848901 | 0.80 | LMNA (0.34) | ALDH1A1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2598540-B2 | — | — | 1997-04-09 | — | — | JP | claimed |
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | claimed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | claimed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | claimed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | claimed |
| EP-1893016-B1 | WATER-IN-OIL SUSPOEMULSIONS | BAYER IP GMBH (DE) | 2017-09-13 | — | — | EP | disclosed |
| EP-1651039-B1 | OIL SUSPENSION CONCENTRATE CONTAINING DIFLUFENICAN | BAYER IP GMBH (DE) | 2017-01-04 | — | — | EP | disclosed |
| US-8318637-B2 | Herbicide/azole combination | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| US-8158557-B2 | Storage-stable formulations of sulfonamides | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| WO-2011076731-A1 | LIQUID FORMULATION OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3,5-TRIAZIN-2-YL)CARBAMOYL]BENZOLSULFONAMIDE | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152082-A1 | LIQUID FORMULATIONS | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-7867946-B2 | Liquid formulation | BAYER CROPSCIENCE AG (DE) | 2011-01-11 | — | — | US | disclosed |
| WO-1995007897-A1 | SUBSTITUTED ISOXAZOLINES, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE AS SAFENERS | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |
| WO-1994026716-A1 | SUBSTITUTED QUINOLINE COMPOUNDS AND THEIR USE AS SAFENERS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-11-24 | — | — | WO | disclosed |
| EP-0582198-A2 | Substituted (hetero-)aryle compounds, process for their preparation, those containing compositions and their use as safeners | Hoechst Schering AgrEvo GmbH (DE) | 1994-02-09 | — | — | EP | disclosed |
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5010195-A | From 5-alkoxy-1,2,4-triazolo(1,5-c)pyrimidine | THE DOW CHEMICAL COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152082-A1 | LIQUID FORMULATIONS | CBX3, CBX6, IPO11 | TSHR 3015/4885FFAR4 4099/4885ALDH1A1 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.