Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 18/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 18/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532623 | 0.90 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL9560009 | 0.83 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1 | |
| SCHEMBL9533019 | 0.83 | LTB4R (0.37) | CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL9533026 | 0.82 | LTB4R (0.41) | CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL9531617 | 0.81 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL9533721 | 0.81 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL9532916 | 0.81 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL10687697 | 0.78 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561574 | 0.75 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL9535168 | 0.73 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |