Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 17/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 17/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560009 | 0.90 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561413 | 0.84 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL10475295 | 0.83 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1 | |
| SCHEMBL9485959 | 0.79 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1 | |
| SCHEMBL9559930 | 0.76 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1 | |
| SCHEMBL9506698 | 0.76 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1 | |
| SCHEMBL9535430 | 0.75 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560080 | 0.75 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9560196 | 0.75 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9484780 | 0.75 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937253-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-26 | — | — | US | claimed |
| EP-0365149-A2 | Leukotriene antagonist prodrugs | SMITHKLINE BEECHAM CORPORATION (US) | 1990-04-25 | — | — | EP | claimed |
| US-5189226-A | Chemical intermediate for diacid | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| US-5034537-A | Alpha-methyl-4-halobenzenemethanamine salts of acids for cardiovascular disorders, respiratory system disorders and antiallergens | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| US-4937253-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0365149-A2 | Leukotriene antagonist prodrugs | SMITHKLINE BEECHAM CORPORATION (US) | 1990-04-25 | — | — | EP | disclosed |
| US-4820719-A | ANTIALLERGENS, ANTIINFLAMMATORY, ANTIISCHEMIC AND HYPOTENSIVE AGENTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |